BDBM790061 2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8,10,11,12,13-hexahydro- 14H-3,5-ethenotripyrazolo[3,4-f:3'',4''- j:4$#8243;,3$#8243;-n][1,4]oxazacyclopentadecin-14- yl]ethan-1-ol::US20250353864, Example 177

SMILES CCOc1nn(CCO)c2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1O[C@@H](C)CN(CC)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 790061   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.230nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.380nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.560nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.670nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 1.08nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 1.56nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 1.78nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 59.1nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent