BDBM790111 2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propan-2-yl)oxy]- 7,8,8a,9,11,17-hexahydro-6H-14,16- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n]pyrrolo[2,1- c][1,4]oxazacyclopentadecin-3(4H)- yl]ethan-1-ol::US20250353864, Example 255

SMILES CC(C)Oc1nn(CCO)c2c1/C=C/c1n[nH]c3cc(F)c(cc13)-c1cnn(C)c1O[C@H](C)[C@H]1CCCN1C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 790111   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 0.270nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 0.820nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 0.950nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 1.18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 1.43nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 1.98nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 3.01nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 4.05nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 6.62nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 9.89nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent