BDBM790129 (2S)-1-{(10S,17E)-12-ethyl-8,10- dimethyl-16-[(propan-2-yl)oxy]- 2,8,10,11,12,13-hexahydro-14H-3,5- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecin-14- yl}propan-2-ol::US20250353864, Example 280

SMILES CCN1Cc2c(c(OC(C)C)nn2C[C@H](C)O)/C=C/c2n[nH]c3ccc(cc23)-c2cnn(C)c2O[C@@H](C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 790129   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790129BDBM790129((2S)-1-{(10S,17E)-12-ethyl-8,10- dimethyl-16-[(pro...)
Affinity DataIC50: 0.240nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790129BDBM790129((2S)-1-{(10S,17E)-12-ethyl-8,10- dimethyl-16-[(pro...)
Affinity DataIC50: 0.520nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetALK tyrosine kinase receptor(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790129BDBM790129((2S)-1-{(10S,17E)-12-ethyl-8,10- dimethyl-16-[(pro...)
Affinity DataIC50: 1.08nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790129BDBM790129((2S)-1-{(10S,17E)-12-ethyl-8,10- dimethyl-16-[(pro...)
Affinity DataIC50: 1.96nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790129BDBM790129((2S)-1-{(10S,17E)-12-ethyl-8,10- dimethyl-16-[(pro...)
Affinity DataIC50: 242nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent