BDBM790142 (10S,13S,17E)-8,10,12,13,14,16- hexamethyl-2,10,11,12,13,14-hexahydro- 8H-3,5-ethenotripyrazolo[3,4-f:3',4'- j:4$#8243;,3$#8243;-n][1,4]oxazacyclopentadecine::US20250353864, Example 145

SMILES Cc1nn(C)c2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1O[C@@H](C)CN(C)[C@H]2C

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 790142   

LigandChemical structure of BindingDB Monomer ID 790142BDBM790142((10S,13S,17E)-8,10,12,13,14,16- hexamethyl-2,10,11...)
Affinity DataIC50: 0.0400nMAssay Description:Table 3: Kinase protein and substrate were pre-diluted in the HEPES assay buffer (100 mM HEPES, pH 7.5, 0.01% Triton X-100, 0.1% BSA, 5 mM MgCl2, 1 m...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 790142BDBM790142((10S,13S,17E)-8,10,12,13,14,16- hexamethyl-2,10,11...)
Affinity DataIC50: 0.210nMAssay Description:Table 3: Kinase protein and substrate were pre-diluted in the HEPES assay buffer (100 mM HEPES, pH 7.5, 0.01% Triton X-100, 0.1% BSA, 5 mM MgCl2, 1 m...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 790142BDBM790142((10S,13S,17E)-8,10,12,13,14,16- hexamethyl-2,10,11...)
Affinity DataIC50: 0.520nMAssay Description:Table 3: Kinase protein and substrate were pre-diluted in the HEPES assay buffer (100 mM HEPES, pH 7.5, 0.01% Triton X-100, 0.1% BSA, 5 mM MgCl2, 1 m...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 790142BDBM790142((10S,13S,17E)-8,10,12,13,14,16- hexamethyl-2,10,11...)
Affinity DataIC50: 99.6nMAssay Description:Table 3: Kinase protein and substrate were pre-diluted in the HEPES assay buffer (100 mM HEPES, pH 7.5, 0.01% Triton X-100, 0.1% BSA, 5 mM MgCl2, 1 m...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details