BDBM790150 (2S)-1-{(10S,17E)-12-ethyl-19-fluoro- 8,10-dimethyl-16-[(propan-2-yl)oxy]- 2,8,10,11,12,13-hexahydro-14H-3,5- ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecin-14- yl}propan-2-ol::US20250353864, Example 296

SMILES CCN1C/C(NC[C@H](C)O)=C(C(=N)OC(C)C)\C=C\c2n[nH]c3cc(F)c(cc23)-c2cnn(C)c2O[C@@H](C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 790150   

TargetDual specificity protein kinase CLK2(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790150BDBM790150((2S)-1-{(10S,17E)-12-ethyl-19-fluoro- 8,10-dimethy...)
Affinity DataIC50: 1.15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790150BDBM790150((2S)-1-{(10S,17E)-12-ethyl-19-fluoro- 8,10-dimethy...)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790150BDBM790150((2S)-1-{(10S,17E)-12-ethyl-19-fluoro- 8,10-dimethy...)
Affinity DataIC50: 1.57nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Homo sapiens)
BLOSSOMHILL THERAPEUTICS, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 790150BDBM790150((2S)-1-{(10S,17E)-12-ethyl-19-fluoro- 8,10-dimethy...)
Affinity DataIC50: 33.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent