BDBM790459 diamix-N-(5-Chloro-2-fluorobenzyl)-2-[(3R)-3''-fluoro-3-methyl[1,4''-bipiperidin]-1''-yl]-1,3-thiazole-5-carboxamide::US12540134, Example 113

SMILES C[C@@H]1CCCN(C2CCN(c3ncc(C(=O)NCc4cc(F)ccc4F)s3)CC2F)C1

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 790459   

TargetAlpha-2C adrenergic receptor(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 790459BDBM790459(diamix-N-(5-Chloro-2-fluorobenzyl)-2-[(3R)-3'-fluo...)
Affinity DataIC50: 0.610nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/15/2026
Entry Details US Patent