BDBM791055 (Z)-2-cyano-N-(2-fluoro-5- (pyrimidin-4-yl)benzyl)-3-hydroxy- 3-(4-hydroxy-3-methoxy-5- nitrophenyl)-N-methylacrylamide::US20260035341, Example 487

SMILES CN(Cc1cc(-c2ccncn2)ccc1F)C(=O)/C(C#N)=C(\O)c1cc(O)c(O)c([N+](=O)[O-])c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791055   

TargetCatechol O-methyltransferase(Human)
Rpxds

US Patent
LigandChemical structure of BindingDB Monomer ID 791055BDBM791055((Z)-2-cyano-N-(2-fluoro-5- (pyrimidin-4-yl)benzyl)...)
Affinity DataIC50: 140nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791055BDBM791055((Z)-2-cyano-N-(2-fluoro-5- (pyrimidin-4-yl)benzyl)...)
Affinity DataIC50: 500nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent