BDBM791062 (Z)-2-cyano-3-(3,4-dihydroxy-5- nitrophenyl)-N-((7- fluoroisoquinolin-6-yl) methyl)-3- hydroxy-N-methylacrylamide::US20260035341, Example 489

SMILES CN(Cc1cc2ccncc2cc1F)C(=O)/C(C#N)=C(O)c1cc(O)c(O)c([N+](=O)[O-])c1

InChI Key InChIKey=FOSRWKXSWAOWOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791062   

TargetCatechol O-methyltransferase(Human)
Rpxds

US Patent
LigandChemical structure of BindingDB Monomer ID 791062BDBM791062((Z)-2-cyano-3-(3,4-dihydroxy-5- nitrophenyl)-N-((7...)
Affinity DataIC50: 250nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 791062BDBM791062((Z)-2-cyano-3-(3,4-dihydroxy-5- nitrophenyl)-N-((7...)
Affinity DataIC50: 710nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2026
Entry Details
US Patent