BDBM791131 ethyl (Z)-2-cyano-3-hydroxy-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylate (Example 639) and ethyl (Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-3-hydroxyacrylate (Example 640)::US20260035341, Example 640

SMILES CCOC(=O)/C(C#N)=C(O)c1cc(OC)c(O)c([N+](=O)[O-])c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791131   

TargetCatechol O-methyltransferase(Human)
Rpxds

US Patent
LigandChemical structure of BindingDB Monomer ID 791131BDBM791131(ethyl (Z)-2-cyano-3-hydroxy-3-(4-hydroxy-3-methoxy...)
Affinity DataIC50: 50nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791131BDBM791131(ethyl (Z)-2-cyano-3-hydroxy-3-(4-hydroxy-3-methoxy...)
Affinity DataIC50: 80nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent