BDBM791134 (Z)-2-(cyclopropanecarbonyl)-3-hydroxy-3-(4-hydroxy-3-methoxy-5-nitrophenyl) acrylonitrile::US20260035341, Example 638

SMILES COc1cc(/C(O)=C(/C#N)C(=O)C2CC2)cc([N+](=O)[O-])c1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791134   

LigandChemical structure of BindingDB Monomer ID 791134BDBM791134((Z)-2-(cyclopropanecarbonyl)-3-hydroxy-3-(4-hydrox...)
Affinity DataIC50: 120nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetCatechol O-methyltransferase(Human)
Rpxds

US Patent
LigandChemical structure of BindingDB Monomer ID 791134BDBM791134((Z)-2-(cyclopropanecarbonyl)-3-hydroxy-3-(4-hydrox...)
Affinity DataIC50: 150nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent