BDBM791186 N-[2-({4-[3-(1H-indol-6-yl)-1H-pyrrolo[3,2-b]pyridin-2-yl]pyridin-3-yl}oxy)ethyl]-N-methylethenesulfonamide::US20260035365, Example 30

SMILES C=CS(=O)(=O)N(C)CCOc1cnccc1-c1[nH]c2cccnc2c1-c1ccc2cc[nH]c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791186   

TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft; The Broad Institute, Inc.; Dana-Farber Cancer Institute, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 791186BDBM791186(N-[2-({4-[3-(1H-indol-6-yl)-1H-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 0.513nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Bayer Aktiengesellschaft; The Broad Institute, Inc.; Dana-Farber Cancer Institute, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 791186BDBM791186(N-[2-({4-[3-(1H-indol-6-yl)-1H-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 1.82nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent