BDBM791192 2-(3-{[(2S)-1-(ethenesulfonyl)pyrrolidin-2-yl]methoxy}pyridin-4-yl)-3-phenyl-1H-pyrrolo[3,2-b]pyridine::US20260035365, Example 36

SMILES C=CS(=O)(=O)N1CCC[C@H]1COc1cnccc1-c1[nH]c2cccnc2c1-c1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791192   

TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft; The Broad Institute, Inc.; Dana-Farber Cancer Institute, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 791192BDBM791192(2-(3-{[(2S)-1-(ethenesulfonyl)pyrrolidin-2-yl]meth...)
Affinity DataIC50: 0.104nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Bayer Aktiengesellschaft; The Broad Institute, Inc.; Dana-Farber Cancer Institute, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 791192BDBM791192(2-(3-{[(2S)-1-(ethenesulfonyl)pyrrolidin-2-yl]meth...)
Affinity DataIC50: 0.308nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent