BDBM791217 N-[2-({4-[3-(2,5-difluorophenyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]pyridin-3-yl}oxy)ethyl]-N-methylethenesulfonamide::US20260035365, Example 61

SMILES C=CS(=O)(=O)N(C)CCOc1cnccc1-c1[nH]c2cccnc2c1-c1cc(F)ccc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791217   

TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft; The Broad Institute, Inc.; Dana-Farber Cancer Institute, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 791217BDBM791217(N-[2-({4-[3-(2,5-difluorophenyl)-1H-pyrrolo[3,2-b]...)
Affinity DataIC50: 0.872nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Bayer Aktiengesellschaft; The Broad Institute, Inc.; Dana-Farber Cancer Institute, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 791217BDBM791217(N-[2-({4-[3-(2,5-difluorophenyl)-1H-pyrrolo[3,2-b]...)
Affinity DataIC50: 2.82nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent