BDBM791657 2-hydroxyethyl (2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)cyclohexyl)methyl)amino)pyrimidin-5-yl)carbamate::US12544374, Compound C17
SMILES O=C(Nc1cnc(NCC2CCC(Nc3ccc4ccnc(Cl)c4n3)CC2)nc1)OCCO
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 791657
TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12(Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 10nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12(Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 88nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
