BDBM791691 2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)cyclohexyl)methyl)amino)pyrimidin-5-yl)-N-(oxetan-3-yl)propanamide::US12544374, Compound C52

SMILES CC(C(=O)NC1COC1)c1cnc(NCC2CCC(Nc3ccc4ccnc(Cl)c4n3)CC2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791691   

LigandChemical structure of BindingDB Monomer ID 791691BDBM791691(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 1nMAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791691BDBM791691(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 30nMAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent