BDBM791696 (R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)cyclohexyl)methyl)amino)pyrimidin-5-yl)-N-methyl-N-(oxetan-3-yl)propanamide::US12544374, Compound C57

SMILES C[C@@H](C(=O)N(C)C1COC1)c1cnc(NCC2CCC(Nc3ccc4ccnc(Cl)c4n3)CC2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791696   

LigandChemical structure of BindingDB Monomer ID 791696BDBM791696((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 3nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791696BDBM791696((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 15nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent