BDBM791699 2-(((4-((8-(methylamino)-1,7-naphthyridin-2-yl)amino)cyclohexyl)methyl)amino)pyrimidine-5-carbonitrile::US12544374, Compound C60

SMILES CNc1nccc2ccc(NC3CCC(CNc4ncc(C#N)cn4)CC3)nc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791699   

LigandChemical structure of BindingDB Monomer ID 791699BDBM791699(2-(((4-((8-(methylamino)-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 21nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791699BDBM791699(2-(((4-((8-(methylamino)-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 22nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent