BDBM791715 (R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)cyclohexyl)methyl)amino)pyrimidin-5-yl)-2-hydroxy-N-(oxetan-3-yl)acetamide::US12544374, Compound C76

SMILES O=C(NC1COC1)[C@H](O)c1cnc(NCC2CCC(Nc3ccc4ccnc(Cl)c4n3)CC2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 791715   

LigandChemical structure of BindingDB Monomer ID 791715BDBM791715((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 5nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791715BDBM791715((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 21nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent