BDBM793688 US20260055079, Example 198

SMILES CC#Cc1ccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N(C)CCN(CC)c4ccc(C#N)cn4)c3)c2c1

InChI Key InChIKey=OFUYTSSYLDWJIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 793688   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Azkarra Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 793688BDBM793688(US20260055079, Example 198)
Affinity DataIC50: 50nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/8/2026
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Azkarra Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 793688BDBM793688(US20260055079, Example 198)
Affinity DataIC50: 2.00E+3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/8/2026
Entry Details
US Patent