BDBM79451 4-(1H-benzimidazol-2-ylthio)-7-(4-methylpiperazino)sulfonyl-piazthiole::7-(1H-benzimidazol-2-ylsulfanyl)-4-(4-methylpiperazin-1-yl)sulfonyl-2,1,3-benzothiadiazole::7-(1H-benzimidazol-2-ylthio)-4-[(4-methyl-1-piperazinyl)sulfonyl]-2,1,3-benzothiadiazole::SR-01000298724::SR-01000298724-2::cid_2236395

SMILES N[C@H]1CC[C@H](N2CCC3CC2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1

InChI Key InChIKey=NSNYNXHVYHCKFB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 79451   

TargetSigma intracellular receptor 2(Human)
University of Texas System

US Patent
LigandChemical structure of BindingDB Monomer ID 79451BDBM79451(US20250387403, Example Table1.29)
Affinity DataKi:  70.5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent