BDBM794971 3-Amino-4-(7-chloro-6-fluoro-1H-indazol-4-yl)-6-cyclopropyl-1H-1,7-phenanthrolin-2-one::US20260062412, Compound C195

SMILES Nc1c(-c2cc(F)c(Cl)c3[nH]ncc23)c2cc(C3CC3)c3ncccc3c2[nH]c1=O

InChI Key InChIKey=XPQKJTUGNBBJRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 794971   

TargetMyelin transcription factor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 794971BDBM794971(3-Amino-4-(7-chloro-6-fluoro-1H-indazol-4-yl)-6-cy...)
Affinity DataIC50: 0.240nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/15/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 794971BDBM794971(3-Amino-4-(7-chloro-6-fluoro-1H-indazol-4-yl)-6-cy...)
Affinity DataIC50: 2.30nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Assay Provider: Laura Bohn External Assay ID: OPRM1_AC...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/15/2026
Entry Details
US Patent