BDBM795190 US12570607, Example 41

SMILES COc1cc(F)ccc1-c1cc(NC(=O)[C@H]2CCC[C@@H](NC(=O)Nc3cc(C)no3)C2)ncc1F

InChI Key InChIKey=ARPYNMZZLGLBRV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 795190   

TargetCyclin-dependent kinase 9(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795190BDBM795190(US12570607, Example 41)
Affinity DataIC50: 7.65nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795190BDBM795190(US12570607, Example 41)
Affinity DataIC50: 196nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 5(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795190BDBM795190(US12570607, Example 41)
Affinity DataIC50: 361nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795190BDBM795190(US12570607, Example 41)
Affinity DataIC50: 629nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795190BDBM795190(US12570607, Example 41)
Affinity DataIC50: 1.08E+3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795190BDBM795190(US12570607, Example 41)
Affinity DataIC50: 1.25E+3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795190BDBM795190(US12570607, Example 41)
Affinity DataIC50: 4.98E+3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent