BDBM795193 US12570607, Example 45

SMILES COc1cc(F)ccc1-c1cc(NC(=O)[C@H]2CCC[C@@H](NC(=O)CO)C2)ncc1F

InChI Key InChIKey=KIRQDLPHJNLSDF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 795193   

TargetCyclin-dependent kinase 9(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795193BDBM795193(US12570607, Example 45)
Affinity DataIC50: 6.92nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795193BDBM795193(US12570607, Example 45)
Affinity DataIC50: 93.2nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 5(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795193BDBM795193(US12570607, Example 45)
Affinity DataIC50: 284nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795193BDBM795193(US12570607, Example 45)
Affinity DataIC50: 564nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795193BDBM795193(US12570607, Example 45)
Affinity DataIC50: 785nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795193BDBM795193(US12570607, Example 45)
Affinity DataIC50: 2.80E+3nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 795193BDBM795193(US12570607, Example 45)
Affinity DataIC50: 4.44E+3nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent