BDBM795215 N-(2- (cyanomethylamino)- 2-oxoethyl)-4- (2-(4- morpholinophenyl- amino)pyrimidin- 4-yl)benzamide::US12570614, Compound 34

SMILES N#CCNC(=O)CNC(=O)c1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1

InChI Key InChIKey=SHACBZUITUQKQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 795215   

TargetTyrosine-protein kinase JAK2(Human)
Glaxosmith Kline

US Patent
LigandChemical structure of BindingDB Monomer ID 795215BDBM795215(N-(2- (cyanomethylamino)- 2-oxoethyl)-4- (2-(4- mo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Glaxosmith Kline

US Patent
LigandChemical structure of BindingDB Monomer ID 795215BDBM795215(N-(2- (cyanomethylamino)- 2-oxoethyl)-4- (2-(4- mo...)
Affinity DataIC50: 5.00E+3nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent