BDBM795268 US12570631, Example 49

SMILES C=CC(=O)N1CCCC1COc1cnccc1-c1ccc(CNC(=O)c2cn(C(C)(C)C)nn2)c(C)c1F

InChI Key InChIKey=MAGRWQYCQWNPCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 795268   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 795268BDBM795268(US12570631, Example 49)
Affinity DataIC50: 5.5nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent