BDBM795311 2-{7-[(1-methyl-1H-indazol-5-yl)amino]-1-oxo-2,3-dihydro-1H-isoindol-2-yl}-N-[3-(trifluoromethyl)phenyl]acetamide::US20260069571, Example 5

SMILES Cn1ncc2cc(Nc3cccc4c3C(=O)N(CC(=O)Nc3cccc(C(F)(F)F)c3)C4)ccc21

InChI Key InChIKey=GXTJZMJLAWKINR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 795311   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 795311BDBM795311(2-{7-[(1-methyl-1H-indazol-5-yl)amino]-1-oxo-2,3-d...)
Affinity DataIC50: 10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 795311BDBM795311(2-{7-[(1-methyl-1H-indazol-5-yl)amino]-1-oxo-2,3-d...)
Affinity DataIC50: 55nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent