BDBM795485 US12570659, Example 80

SMILES CC(=O)N[C@H]1CC[C@H](NC(=O)c2cnn3c(Cl)c(-c4ccncc4)cc3c2NC(C)C)CC1

InChI Key InChIKey=TZTALEVGRHEKMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 795485   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795485BDBM795485(US12570659, Example 80)
Affinity DataIC50: 2nMAssay Description:The assay involves using a cell line that expresses the NR1 subunit together with either NR2C or NR2D. These cell lines can be prepared by transfecti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795485BDBM795485(US12570659, Example 80)
Affinity DataIC50: 3.50E+4nMAssay Description:The assay involves using a cell line that expresses the NR1 subunit together with either NR2C or NR2D. These cell lines can be prepared by transfecti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent