BDBM795527 US12570659, Example 123

SMILES CC(C)Nc1c(C(=O)NC[C@@H](F)C(C)(C)O)cnc2cc(-c3ccc(=O)[nH]c3)nn12

InChI Key InChIKey=IRAOHTSFPOBTRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 795527   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795527BDBM795527(US12570659, Example 123)
Affinity DataIC50: 4.90nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795527BDBM795527(US12570659, Example 123)
Affinity DataIC50: 5.00E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent