BDBM795796 ((1R)-1-(5-(3-chlorobenzyl)-3-((1-isopropyl-3-methyl-1H-pyrazol-5-carboxamido)methyl)-4,5-dihydroisoxazol-5-carboxamido)-3-methylbutyl)boronic acid::US12570675, Example 225

SMILES Cc1cc(C(=O)NCC2=NOC(Cc3cccc(Cl)c3)(C(=O)N[C@@H](CC(C)C)B(O)O)C2)n(C(C)C)n1

InChI Key InChIKey=DXYNLZKIHANAIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 795796   

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795796BDBM795796(((1R)-1-(5-(3-chlorobenzyl)-3-((1-isopropyl-3-meth...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent