BDBM796361 4-(2-(((3R,4R)-3- hydroxy-1- (methylsulfonyl)piperidin- 4-yl)amino)pyrrolo[2,1- f][1,2,4]triazin-6-yl)-1H- pyrazole-5-carbonitrile::US20260070914, Example 66

SMILES CS(=O)(=O)N1CC[C@@H](Nc2ncc3cc(-c4cn[nH]c4C#N)cn3n2)[C@H](O)C1

InChI Key InChIKey=OGCYYDHZQPXHEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 796361   

LigandChemical structure of BindingDB Monomer ID 796361BDBM796361(4-(2-(((3R,4R)-3- hydroxy-1- (methylsulfonyl)piper...)
Affinity DataIC50: 10nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796361BDBM796361(4-(2-(((3R,4R)-3- hydroxy-1- (methylsulfonyl)piper...)
Affinity DataIC50: 55nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent