BDBM79824 5-bromanyl-3,3-bis(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-7-methyl-1H-indol-2-one::5-bromo-3,3-bis(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-7-methyl-1,3-dihydro-2H-indol-2-one::5-bromo-3,3-bis(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-7-methyl-1H-indol-2-one::5-bromo-3,3-bis(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-7-methyl-1H-indol-2-one::5-bromo-3,3-bis(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-7-methyl-oxindole::MLS000548055::SMR000114179::cid_4420032

SMILES COc1ccccc1-c1ccc(C(=O)N(C)CC2CCOC2)c(S(C)(=O)=O)c1

InChI Key InChIKey=AWYHAJSPPSBCPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 79824   

TargetE3 ubiquitin-protein ligase TRIM21(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79824BDBM79824(US20250388560, Compound 25)
Affinity DataKd:  5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent