BDBM798305 US20260078114, Compound TB-42

SMILES CN1CCCn5c1nc4c(F)cc(c3nc(N[C@@H]2CCOC[C@H]2O)ncc3F)cc45

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 798305   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798305BDBM798305(US20260078114, Compound TB-42)
Affinity DataIC50: 8.36nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798305BDBM798305(US20260078114, Compound TB-42)
Affinity DataIC50: 195nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent