BDBM79860 (2S)-3-(1H-indol-3-yl)-2-(2-thenoylamino)propionic acid [2-keto-2-(p-anisylamino)ethyl] ester::(2S)-3-(1H-indol-3-yl)-2-[[oxo(thiophen-2-yl)methyl]amino]propanoic acid [2-[(4-methoxyphenyl)methylamino]-2-oxoethyl] ester::MLS000392491::SMR000261397::[2-[(4-methoxyphenyl)methylamino]-2-oxidanylidene-ethyl] (2S)-3-(1H-indol-3-yl)-2-(thiophen-2-ylcarbonylamino)propanoate::[2-[(4-methoxyphenyl)methylamino]-2-oxoethyl] (2S)-3-(1H-indol-3-yl)-2-(thiophene-2-carbonylamino)propanoate::cid_15945167

SMILES CSc1cc(F)ccc1-c1ccc(C(=O)N(C)CC2CCOCC2)c(S(C)(=O)=O)c1

InChI Key InChIKey=FAWYIQXHIRKEBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 79860   

TargetE3 ubiquitin-protein ligase TRIM21(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79860BDBM79860(US20250388560, Compound 55)
Affinity DataKd: <10nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent