BDBM79869 MLS000401526::N-(2-chlorophenyl)-3-[[(2-ketoindol-3-yl)amino]carbamoyl]benzenesulfonamide::N-(2-chlorophenyl)-3-[[(2-oxidanylideneindol-3-yl)amino]carbamoyl]benzenesulfonamide::N-(2-chlorophenyl)-3-[[(2-oxoindol-3-yl)amino]carbamoyl]benzenesulfonamide::N-(2-chlorophenyl)-3-[oxo-[(2-oxo-3-indolyl)hydrazo]methyl]benzenesulfonamide::SMR000243241::cid_5853451

SMILES Cc1[nH]c(/C=C2C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccccc4)cc32)c(C)c1C(=O)N[C@@H]1c2ccccc2C[C@@H]1O

InChI Key InChIKey=AFPQKCVQSKKKEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79869   

TargetG protein-coupled receptor kinase 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79869BDBM79869(US20250388567, Compound 5)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Bovine)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79869BDBM79869(US20250388567, Compound 5)
Affinity DataIC50: 1.00E+4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent