BDBM79874 MLS000723692::N'-[(1E,2Z)-2-bromo-3-phenylprop-2-enylidene]-3-(5-methyl-2-furyl)-1H-pyrazole-5-carbohydrazide::N-[[(Z)-2-bromanyl-3-phenyl-prop-2-enylidene]amino]-5-(5-methylfuran-2-yl)-1H-pyrazole-3-carboxamide::N-[[(Z)-2-bromo-3-phenyl-prop-2-enylidene]amino]-5-(5-methyl-2-furyl)-1H-pyrazole-3-carboxamide::N-[[(Z)-2-bromo-3-phenylprop-2-enylidene]amino]-5-(5-methyl-2-furanyl)-1H-pyrazole-3-carboxamide::N-[[(Z)-2-bromo-3-phenylprop-2-enylidene]amino]-5-(5-methylfuran-2-yl)-1H-pyrazole-3-carboxamide::SMR000305287::cid_16193452

SMILES Cc1[nH]c(/C=C2C(=O)Nc3ccc(C(=O)N[C@@H]4CCc5ccccc54)cc32)c(C)c1NC(=O)C(O)c1ccco1

InChI Key InChIKey=NECFKNBGKKRENB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79874   

TargetG protein-coupled receptor kinase 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79874BDBM79874(US20250388567, Compound 10)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Bovine)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79874BDBM79874(US20250388567, Compound 10)
Affinity DataIC50: 1.00E+4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent