BDBM79879 2-[3-(2,5-dimethyl-1-pyrrolyl)-2-thiophenyl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one::2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)-2-thienyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-ol::2-[3-(2,5-dimethylpyrrol-1-yl)-2-thienyl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one::2-[3-(2,5-dimethylpyrrol-1-yl)thiophen-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one::MLS000736290::SMR000338240::cid_4360235

SMILES Cc1[nH]c(/C=C2C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccc(F)cc4)cc32)c(C)c1NC(=O)[C@H](O)c1ccco1

InChI Key InChIKey=XSBCFLGDNDHVIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79879   

TargetG protein-coupled receptor kinase 5(Human)
Purdue Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 79879BDBM79879(US20250388567, Compound 15)
Affinity DataIC50: 5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Bovine)
Purdue Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 79879BDBM79879(US20250388567, Compound 15)
Affinity DataIC50: 5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent