BDBM79898 4-amino-3-methyl-N'-(phenylmethylene)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carbohydrazide::4-amino-3-methyl-N-[(phenylmethylene)amino]-2-sulfanylidene-5-thiazolecarboxamide::4-amino-N-(benzalamino)-3-methyl-2-thioxo-4-thiazoline-5-carboxamide::4-amino-N-(benzylideneamino)-3-methyl-2-sulfanylidene-1,3-thiazole-5-carboxamide::4-azanyl-3-methyl-N-[(phenylmethylidene)amino]-2-sulfanylidene-1,3-thiazole-5-carboxamide::MLS000860559::SMR000458643::cid_2813734

SMILES Cc1[nH]c(/C=C2C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccccc4)cc32)c(C)c1C(=O)NCC(O)c1ccoc1

InChI Key InChIKey=FDULOSNQQBHPAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79898   

TargetG protein-coupled receptor kinase 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79898BDBM79898(US20250388567, Compound 32)
Affinity DataIC50: 100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Bovine)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79898BDBM79898(US20250388567, Compound 32)
Affinity DataIC50: 5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent