BDBM79899 MLS000518522::N-[2-(2-chlorophenyl)-5-hydroxy-4-keto-chromen-8-yl]-3,5-dimethyl-isoxazole-4-sulfonamide::N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo-1-benzopyran-8-yl]-3,5-dimethyl-4-isoxazolesulfonamide::N-[2-(2-chlorophenyl)-5-hydroxy-4-oxochromen-8-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide::N-[2-(2-chlorophenyl)-5-oxidanyl-4-oxidanylidene-chromen-8-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide::SMR000465241::cid_16060398

SMILES Cc1[nH]c(/C=C2C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccccc4)cc32)c(C)c1C(=O)Nc1nc2ccccc2[nH]1

InChI Key InChIKey=XKYBPHWVOXMRHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79899   

TargetG protein-coupled receptor kinase 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79899BDBM79899(US20250388567, Compound 33)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Bovine)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79899BDBM79899(US20250388567, Compound 33)
Affinity DataIC50: 5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent