BDBM79907 5-(2-Chloro-phenyl)-isoxazole-3-carboxylic acid (2-hydroxy-5-methyl-phenyl)-amide::5-(2-chlorophenyl)-N-(2-hydroxy-5-methyl-phenyl)isoxazole-3-carboxamide::5-(2-chlorophenyl)-N-(2-hydroxy-5-methylphenyl)-1,2-oxazole-3-carboxamide::5-(2-chlorophenyl)-N-(2-hydroxy-5-methylphenyl)-3-isoxazolecarboxamide::5-(2-chlorophenyl)-N-(5-methyl-2-oxidanyl-phenyl)-1,2-oxazole-3-carboxamide::MLS001202480::SMR000524508::cid_1093851

SMILES Cc1[nH]c(/C=C2C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccccc4)cc32)c(C)c1C(=O)NC[C@@H]1CCCO1

InChI Key InChIKey=MOGPCFGJLJCFNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79907   

TargetG protein-coupled receptor kinase 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79907BDBM79907(US20250388567, Compound 37)
Affinity DataIC50: 100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Bovine)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79907BDBM79907(US20250388567, Compound 37)
Affinity DataIC50: 5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent