BDBM79919 3-(2-chlorophenyl)-2-sulfanylidene-1-[(3,4,5-trimethoxyphenyl)methyl]-4-imidazolidinone::3-(2-chlorophenyl)-2-sulfanylidene-1-[(3,4,5-trimethoxyphenyl)methyl]imidazolidin-4-one::3-(2-chlorophenyl)-2-thioxo-1-(3,4,5-trimethoxybenzyl)-4-imidazolidinone::3-(2-chlorophenyl)-2-thioxo-1-(3,4,5-trimethoxybenzyl)imidazolidin-4-one::MLS001200914::SMR000564417::cid_4581175

SMILES Cc1ccc(C(O)(C(N)=O)C(F)(F)F)cc1-c1cnc(N)c(N2CCN(c3ccccc3C#N)CC2)n1

InChI Key InChIKey=IVCXDKINXIVSAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79919   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79919BDBM79919(2-(3-(5 -amino-6-(4-(2- cyanophcnyl)piperazin-1- y...)
Affinity DataIC50: 100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79919BDBM79919(2-(3-(5 -amino-6-(4-(2- cyanophcnyl)piperazin-1- y...)
Affinity DataIC50: 100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent