BDBM79920 2-(3-acetamidophenoxy)-N-(1-naphthalen-2-ylethyl)acetamide::2-(3-acetamidophenoxy)-N-(1-naphthalen-2-ylethyl)ethanamide::2-(3-acetamidophenoxy)-N-[1-(2-naphthalenyl)ethyl]acetamide::2-(3-acetamidophenoxy)-N-[1-(2-naphthyl)ethyl]acetamide::MLS001177268::SMR000592055::cid_16338637

SMILES CN1CCN(c2ccc(-c3ccc4c(c3)C(=O)N(C(C(=O)Nc3nccs3)c3cccc(F)c3)CO4)cc2)CC1

InChI Key InChIKey=ABSPCBSIRGQAKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79920   

TargetEpidermal growth factor receptor [T790M,L858R](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79920BDBM79920(US20250388573, Compound 002)
Affinity DataIC50: 4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79920BDBM79920(US20250388573, Compound 002)
Affinity DataIC50: 23nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent