BDBM79921 1H-indol-2-yl-(4-tosyl-1,4-diazepan-1-yl)methanone::1H-indol-2-yl-[4-(4-methylphenyl)sulfonyl-1,4-diazepan-1-yl]methanone::MLS001172054::SMR000596329::cid_9397654

SMILES CN1CCC(c2ccc(-c3ccc4c(c3)C(=O)N(C(C(=O)Nc3nccs3)c3ccccc3)CO4)cc2)CC1

InChI Key InChIKey=QELJUVYWWJBVSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79921   

TargetEpidermal growth factor receptor [T790M,L858R](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79921BDBM79921(US20250388573, Compound 003)
Affinity DataIC50: 0.800nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79921BDBM79921(US20250388573, Compound 003)
Affinity DataIC50: 23nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent