BDBM79922 (2,5-dimethylphenyl)-diphenoxyphosphoryl-amine::MLS001170948::N-diphenoxyphosphoryl-2,5-dimethyl-aniline::N-diphenoxyphosphoryl-2,5-dimethylaniline::SMR000589417::cid_2305273

SMILES CN1CCC(c2ccc(-c3ccc4c(c3)OCN(C(C(=O)Nc3nccs3)c3ccccc3)C4=O)cc2)CC1

InChI Key InChIKey=GMSMBWMTBLESFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79922   

TargetEpidermal growth factor receptor [T790M,L858R](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79922BDBM79922(US20250388573, Compound 004)
Affinity DataIC50: 21nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79922BDBM79922(US20250388573, Compound 004)
Affinity DataIC50: 100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent