BDBM79937 MLS001090469::SMR000659309::[3-(3,4-dimethylanilino)-1-piperidinyl]-(1-methyl-3-indolyl)methanone::[3-(3,4-dimethylanilino)piperidin-1-yl]-(1-methylindol-3-yl)methanone::[3-(3,4-dimethylanilino)piperidino]-(1-methylindol-3-yl)methanone::[3-[(3,4-dimethylphenyl)amino]piperidin-1-yl]-(1-methylindol-3-yl)methanone::cid_24817165

SMILES CCS(=O)(=O)Cc1ccc(Oc2cccc(CCCCC3CCN(c4ncc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)cn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1

InChI Key InChIKey=ZLZVMUYNIGEFMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 79937   

TargetAndrogen receptor(Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79937BDBM79937(US20250388575, Compound I-158)
Affinity DataKd: <10nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79937BDBM79937(US20250388575, Compound I-158)
Affinity DataKd:  55nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79937BDBM79937(US20250388575, Compound I-158)
Affinity DataKd:  55nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetProgesterone receptor ligand binding domain (LBD)(Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79937BDBM79937(US20250388575, Compound I-158)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent