BDBM801982 US20260108512, Compound 1

SMILES CC(C)[C@H]1CN(C)CCN1Cc1cc(C(F)(F)F)c2cn(-c3cccc(C4(Cc5nncn5C(F)F)COC4)c3)c(=O)n2c1

InChI Key InChIKey=QZQIYFGZEYLRAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801982   

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801982BDBM801982(US20260108512, Compound 1)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent