BDBM802011 US20260108512, Compound 6

SMILES Cn1cnnc1[C@@H](F)[C@](C)(F)c1cccc(-n2cc3c(C(F)(F)F)cc(CN4CCC5(CC5)C4)cn3c2=O)c1

InChI Key InChIKey=VDCIBZOQXJHABV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802011   

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802011BDBM802011(US20260108512, Compound 6)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent