BDBM802049 US20260108512, Compound 14

SMILES Cn1cnnc1[C@H](F)C1(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CC(C)(CO)C5)cn4c3=O)c2)COC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802049   

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802049BDBM802049(US20260108512, Compound 14)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent