BDBM802057 (2S,4R)-1-((S)-3-cyclopropyl- 7,8-dihydro-4H,6H-[1,2,3] triazolo[5,1-c][1,4]oxazepine- 8-carbonyl)-4-hydroxy-N-((S)- 1-(4-(4-methyl-thiazol-5-yl)- phenyl)ethyl)pyrrolidine-2- carboxamide::US20260108613, Compound A1

SMILES Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H]2CCOCc3c(C4CC4)nnn32)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802057   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 802057BDBM802057((2S,4R)-1-((S)-3-cyclopropyl- 7,8-dihydro-4H,6H-[1...)
Affinity DataIC50: 354nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent