BDBM802068 US20260108613, Compound A13::methyl (S)-3-((2S,4R)-1- ((7S,8S)-3-cyclopropyl-7- methyl-7,8-dihydro-4H,6H- [1,2,3]triazolo[5,1-c][1,4] oxazepine-8-carbonyl)-4- hydroxypyrrolidine-2-carbox- amido)-3-(4-(4-methylthiazol- 5-yl)phenyl)propanoate

SMILES COC(=O)C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H]1[C@H](C)COCc2c(C3CC3)nnn21)c1ccc(-c2scnc2C)cc1

InChI Key InChIKey=MWPPSHUGCIHGTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802068   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 802068BDBM802068(methyl (S)-3-((2S,4R)-1- ((7S,8S)-3-cyclopropyl-7-...)
Affinity DataIC50: 33nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent