BDBM802069 methyl (S)-3-((2S,4R)-1- ((7R,8S)-5-benzyl-3,7-dimeth- yl-5,6,7,8-tetrahydro-4H- [1,2,3]triazolo[1,5-a][1,4] diazepine-8-carbonyl)-4- hydroxypyrrolidine-2-carbox- amido)-3-(4-(4-methylthiazol- 5-yl)phenyl)propanoate::US20260108613, Compound A14

SMILES COC(=O)C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H]1[C@H](C)CN(Cc2ccccc2)Cc2c(C)nnn21)c1ccc(-c2scnc2C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802069   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 802069BDBM802069(methyl (S)-3-((2S,4R)-1- ((7R,8S)-5-benzyl-3,7-dim...)
Affinity DataIC50: 58nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent